Dave Kendall

Contact

• workRoom E71 University of Nottingham Medical School
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• dave.kendall@nottingham.ac.uk

Research Summary

In vitro pharmacological approaches to the study of G protein-coupled receptors: radioligand binding, autoradiography, 2nd messenger assays (cAMP, cGMP, inositol phosphates) intracellular Ca2+… read more

Recent Publications

• PRIESTLEY RS, NICKOLLS SA, ALEXANDER SPH and KENDALL DA, 2015. A potential role for cannabinoid receptors in the therapeutic action of fenofibrate. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(4), 1446-55
• HASSAN S, ELDEEB K, MILLNS PJ, BENNETT AJ, ALEXANDER SPH and KENDALL DA, 2014. Cannabidiol enhances microglial phagocytosis via transient receptor potential (TRP) channel activation. British journal of pharmacology. 171(9), 2426-39
• EBADA, MOHAMED ELSAED, LATIF, LIAQUE M., KENDALL, DAVID A. and PARDON, MARIE-CHRISTINE, 2014. Corticosterone protects against memory impairments and reduced hippocampal BDNF levels induced by a chronic low dose of ethanol in C57BL/6J mice ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY. 55(4), 1303-1316
• MAROOF, NAZIA, RAVIPATI, SRINIVASARAO, PARDON, MARIE CHRISTINE, BARRETT, DAVID A. and KENDALL, DAVID A., 2014. Reductions in Endocannabinoid Levels and Enhanced Coupling of Cannabinoid Receptors in the Striatum are Accompanied by Cognitive Impairments in the A beta PPswe/PS1 Delta E9 Mouse Model of Alzheimer's Disease JOURNAL OF ALZHEIMERS DISEASE. 42(1), 227-245

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Current Research

In vitro pharmacological approaches to the study of G protein-coupled receptors: radioligand binding, autoradiography, 2nd messenger assays (cAMP, cGMP, inositol phosphates) intracellular Ca2+ measurements, immunohistochemistry, reporter gene assays, Western blotting, primary cell culture. confocal microscopy. Classical pharmacological preparations: isolated blood vessels and other smooth muscle preparations.

Future Research

Interests in chemical analysis of small lipids such as anandamide, 2-arachidonyl glycerol and lysophosphatidic acid.

• PRIESTLEY RS, NICKOLLS SA, ALEXANDER SPH and KENDALL DA, 2015. A potential role for cannabinoid receptors in the therapeutic action of fenofibrate. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(4), 1446-55
• HASSAN S, ELDEEB K, MILLNS PJ, BENNETT AJ, ALEXANDER SPH and KENDALL DA, 2014. Cannabidiol enhances microglial phagocytosis via transient receptor potential (TRP) channel activation. British journal of pharmacology. 171(9), 2426-39
• EBADA, MOHAMED ELSAED, LATIF, LIAQUE M., KENDALL, DAVID A. and PARDON, MARIE-CHRISTINE, 2014. Corticosterone protects against memory impairments and reduced hippocampal BDNF levels induced by a chronic low dose of ethanol in C57BL/6J mice ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY. 55(4), 1303-1316
• MAROOF, NAZIA, RAVIPATI, SRINIVASARAO, PARDON, MARIE CHRISTINE, BARRETT, DAVID A. and KENDALL, DAVID A., 2014. Reductions in Endocannabinoid Levels and Enhanced Coupling of Cannabinoid Receptors in the Striatum are Accompanied by Cognitive Impairments in the A beta PPswe/PS1 Delta E9 Mouse Model of Alzheimer's Disease JOURNAL OF ALZHEIMERS DISEASE. 42(1), 227-245
• KING, MADELEINE V., KURIAN, NISHA, QIN, SI, PAPADOPOULOU, NEKTARIA, WESTERINK, BEN H. C., CREMERS, THOMAS I., EPPING-JORDAN, MARK P., LE POUL, EMMANUEL, RAY, DAVID E., FONE, KEVIN C. F., KENDALL, DAVID A., MARSDEN, CHARLES A. and SHARP, TYSON V., 2014. Lentiviral Delivery of a Vesicular Glutamate Transporter 1 (VGLUT1)-Targeting Short Hairpin RNA Vector Into the Mouse Hippocampus Impairs Cognition NEUROPSYCHOPHARMACOLOGY. 39(2), 464-476
• WONG, AMY, SAGAR, DEVI R., ORTORI, CATHARINE A., KENDALL, DAVID A., CHAPMAN, VICTORIA and BARRETT, DAVID A., 2014. Simultaneous tissue profiling of eicosanoid and endocannabinoid lipid families in a rat model of osteoarthritis JOURNAL OF LIPID RESEARCH. 55(9), 1902-1913
• WONG, RAYMOND, GIBSON, CLAIRE L., KENDALL, DAVID A. and BATH, PHILIP M. W., 2014. Evaluating the translational potential of progesterone treatment following transient cerebral ischaemia in male mice BMC NEUROSCIENCE. 15,
• ALSALEM, M., WONG, A., MILLNS, P., ARYA, P.H., CHAN, M.S.L., BENNETT, A., BARRETT, D.A., CHAPMAN, V. and KENDALL, D.A., 2013. The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms British Journal of Pharmacology. 168(8), 1961-1974
• BUTLER RK, FORD GK, HOGAN M, ROCHE M, DOYLE KM, KELLY JP, KENDALL DA, CHAPMAN V and FINN DP, 2012. Fear-Induced Suppression Of Nociceptive Behaviour And Activation Of Akt Signalling In The Rat Periaqueductal Grey: Role Of Fatty Acid Amide Hydrolase. Journal Of Psychopharmacology (Oxford, England). 26(1), 83-91
• SAGAR DR, BURSTON JJ, HATHWAY GJ, WOODHAMS SG, PEARSON RG, BENNETT AJ, KENDALL DA, SCAMMELL BE AND CHAPMAN V, 2012. Evidence for a contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain Mol.Pain. (In Press.)
• ASSARAH N, EL BATSH M, MARSDEN CA, KENDALL DA, 2012. The effects of chronic administration of tranylcypromine and rimonabant on behaviour and protein expression in brain regions of the rat Pharmacology, Biochemistry and Behavior. (In Press.)
• ABDUL AZIZ NHK, KENDALL DA PARDON M-C, 2012. Prenatal exposure to chronic mild stress increases corticosterone levels in the amniotic fluid and induces cognitive deficits in female offspring, reversible by treatment with the antidepressant drug amitriptyline. J. Neuroendocrin.. (In Press.)
• OKINE BN, NORRIS LM, WOODHAMS S, BURSTON J, PATEL A, ALEXANDER SPH, BARRETT DA, KENDALL DA, BENNETT AJ and CHAPMAN V, 2012. Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. British journal of pharmacology. 167(3), 627-40
• ABDUL AZIZ NHK, KENDALL DA and PARDON M, 2012. Prenatal exposure to chronic mild stress increases corticosterone levels in the amniotic fluid and induces cognitive deficits in female offspring, improved by treatment with the antidepressant drug amitriptyline. Behavioural brain research. 231(1), 29-39
• ELBATSH MM, MOKLAS MAA, MARSDEN CA and KENDALL DA, 2012. Antidepressant-like effects of Δ⁹-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression. Pharmacology, biochemistry, and behavior. 102(2), 357-65
• ELBATSH M.M., ASSAREH N., MARSDEN C.A. and KENDALL D.A., 2012. Anxiogenic-like effects of chronic cannabidiol administration in rats Psychopharmacology. 221(2), 239-247
• WONG R, RAY D and KENDALL DA, 2012. Progesterone pharmacokinetics in the mouse: implications for potential stroke therapy. The Journal of pharmacy and pharmacology. 64(11), 1614-20
• CULSHAW J, KENDALL D and WILCOCK A, 2012. Off-label prescribing in palliative care: A survey of independent prescribers. Palliative medicine. (In Press.)
• SARMAD, S., ALEXANDER, S.P.H., BARRETT, D.A., MARSDEN, C.A. and KENDALL, D.A., 2011. Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices Journal of Neurochemistry. 117(4), 665-677
• ABDEL-RAZAQ W, KENDALL DA and BATES TE, 2011. The Effects Of Antidepressants On Mitochondrial Function In A Model Cell System And Isolated Mitochondria. Neurochemical Research. 36(2), 327-38
• O’SULLIVAN SE, KENDALL PJ AND KENDALL DA, 2011. Endocannabinoids and the cardiovascular response to stress J.Psychopharmacol.. (In Press.)
• SAGAR, DEVI RANI, JHAVERI, MAULIK D, RICHARDSON, DENISE, GRAY, ROY A, DE LAGO, EVA, FERNÁNDEZ-RUIZ, JAVIER, BARRETT, DAVID A, KENDALL, DAVID A and CHAPMAN, VICTORIA, 2010. Endocannabinoid regulation of spinal nociceptive processing in a model of neuropathic pain. The European journal of neuroscience. 31(8), 1414-22
• STANIASZEK, L.E., NORRIS, L.M., KENDALL, D.A., BARRETT, D.A. and CHAPMAN, V., 2010. Effects of COX-2 inhibition on spinal nociception: the role of endocannabinoids British Journal of Pharmacology. 160(3), 669-676
• O'SULLIVAN, SE and KENDALL, DA, 2010. Cannabinoid Activation Of Peroxisome Proliferator-Activated Receptors: Potential For Modulation Of Inflammatory Disease Immunobiology. 215(8), 611-616
• SAGAR, D.R., STANIASZEK, L.E., OKINE, B.N., WOODHAMS, S., NORRIS, L.M., PEARSON, R.G., GARLE, M.J., ALEXANDER, S.P.H., BENNETT, A.J., BARRETT, D.A., KENDALL, D.A., SCAMMELL, B.E. and CHAPMAN, V., 2010. Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain Arthritis & Rheumatism. 62(12), 3666-3676
• PARDON, M.C., SARMAD, S., RATTRAY, I., BATES, T.E., SCULLION, G.A., MARSDEN, C.A., BARRETT, D.A., LOWE, J. and KENDALL, D.A., 2009. Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels Neurobiology of Aging. 30(7), 1099-1113
• GUASTI, L., RICHARDSON, D., JHAVERI, M., ELDEEB, K., BARRETT, D., ELPHICK, M.R., ALEXANDER, S.P.H., KENDALL, D., MICHAEL, G.J. and CHAPMAN, V., 2009. Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain Molecular Pain. 5, 35
• SCULLION, G.A., KENDALL, D.A., SUNTER, D., MARSDEN, C.A. and PARDON, M.-C., 2009. Central noradrenergic depletion by DSP-4 prevents stress-induced memory impairments in the object recognition task. Neuroscience. 164(2), 415-423
• O'SULLIVAN, S.E., SUN, Y., BENNETT, A.J., RANDALL, M.D. and KENDALL, D.A., 2009. Time-dependent vascular actions of cannabidiol in the rat aorta European Journal of Pharmacology. 612(1-3), 61-68
• JONES, K.L., FINN, D.P., GOVERNO, R.J.M., PRIOR, M.J., MORRIS, P.G., KENDALL, D.A., MARSDEN, C.A. and CHAPMAN, V., 2009. Identification of discrete sites of action of chronic treatment with desipramine in a model of neuropathic pain Neuropharmacology. 56(2), 405-413
• RATTRAY, I, SCULLION, GA, SOULBY, A, KENDALL, DA and PARDON, MC, 2009. The Occurrence Of A Deficit In Contextual Fear Extinction In Adult Amyloid-Over-Expressing Tastpm Mice Is Independent Of The Strength Of Conditioning But Can Be Prevented By Mild Novel Cage Stress Behavioural Brain Research. 200(1), 83-90
• O'SULLIVAN, SE, KENDALL, DA and RANDALL, AD, 2009. Time-Dependent Vascular Effects Of Endocannabinoids Mediated By Peroxisome Proliferator-Activated Receptor Gamma (Ppar Gamma) Ppar Research. -
• JEAN-GILLES, L, FENG, S, TENCH, CR, CHAPMAN, V, KENDALL, DA, BARRETT, DA and CONSTANTINESCU, CS, 2009. Plasma Endocannabinoid Levels In Multiple Sclerosis Journal Of The Neurological Sciences. 287(1-2), 212-215
• RALEVIC V and KENDALL DA, 2009. Cannabinoid Modulation Of Perivascular Sympathetic And Sensory Neurotransmission. Current Vascular Pharmacology. 7(1), 15-25
• SAGAR, DR, GAW, AG, OKINE, BN, WOODHAMS, SG, WONG, A, KENDALL, DA and CHAPMAN, V, 2009. Dynamic Regulation Of The Endocannabinoid System: Implications For Analgesia
• JHAVERI, M.D., RICHARDSON, D., ROBINSON, I., GARLE, M.J., PATEL, A., SUN, Y., SAGAR, D.R., BENNETT, A.J., ALEXANDER, S.P.H., KENDALL, D.A., BARRETT, D.A. and CHAPMAN, V., 2008. Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain Neuropharmacology. 55(1), 85-93
• PEARSON, R.G., RICHARDSON, D., KURIAN, N., LATIF, M.L., GARLE, M.J., BARRETT, D.A., KENDALL, D.A., SCAMMELL, B.E., REEVE, A.J. and CHAPMAN, V., 2008. Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis Arthritis Research & Therapy. 10(2), R43
• JHAVERI, M D, ELMES, S J R, RICHARDSON, D, BARRETT, D A, KENDALL, D A, MASON, R and CHAPMAN, V, 2008. Evidence for a novel functional role of cannabinoid CB(2) receptors in the thalamus of neuropathic rats. The European journal of neuroscience. 27(7), 1722-30
• BRIGNELL, JENNIFER L, CHAPMAN, VICTORIA and KENDALL, DAVID A, 2008. Comparison of icilin- and cold-evoked responses of spinal neurones, and their modulation of mechanical activity, in a model of neuropathic pain. Brain Research. 1215, 87-96
• SAGAR, D.R., KENDALL, D.A. and CHAPMAN, V., 2008. Inhibition of fatty acid amide hydrolase produces PPAR-α-mediated analgesia in a rat model of inflammatory pain British Journal of Pharmacology. 155(8), 1297-1306
• DE BANK, P.A., HOU,Q., WARNER, R.M., WOOD, I.V., ALI, B.E., MACNEIL, S., KENDALL, D.A., KELLAM, B.K., SHAKESHEFF, K.M. and BUTTERY, L.D.K., 2007. Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking Biotechnology and Bioengineering. 97(6), 1617-1625
• ATHANASIOU, ANDRIANI, SMITH, PAUL A, VAKILPOUR, SARA, KUMARAN, NETHIA M, TURNER, AMY E, BAGIOKOU, DIMITRA, LAYFIELD, ROBERT, RAY, DAVID E, WESTWELL, ANDREW D, ALEXANDER, STEPHEN P H and KENDALL, DAVID A, 2007. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications. 354(1), 50-5
• ATHANASIOU, ANDRIANI, CLARKE, ANNA B, TURNER, AMY E, KUMARAN, NETHIA M, VAKILPOUR, SARA, SMITH, PAUL A, BAGIOKOU, DIMITRA, BRADSHAW, TRACEY D, WESTWELL, ANDREW D, FANG, LIN, LOBO, DILEEP N and CONSTANTIN, 2007. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and biophysical research communications. 364(1), 131-7
• SUN, Y, ALEXANDER, S P H, GARLE, M J, GIBSON, C L, HEWITT, K, MURPHY, S P, KENDALL, D A and BENNETT, A J, 2007. Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism. British Journal of Pharmacology. 152(5), 734-43
• RANDALL, MICHAEL D, KENDALL, DAVID A, BENNETT, ANDREW J and O'SULLIVAN, SAOIRSE E, 2007. Rimonabant in obese patients with type 2 diabetes. Lancet. 369(9561), 555
• RICHARDSON, DENISE, ORTORI, CATHARINE A, CHAPMAN, VICTORIA, KENDALL, DAVID A and BARRETT, DAVID A, 2007. Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. Analytical Biochemistry. 360(2), 216-26
• JHAVERI, MAULIK D, SAGAR, DEVI R, ELMES, STEVEN J R, KENDALL, DAVID A and CHAPMAN, VICTORIA, 2007. Cannabinoid CB2 receptor-mediated anti-nociception in models of acute and chronic pain. Molecular Neurobiology. 36(1), 26-35
• ALEXANDER, SPH and KENDALL, DA, 2007. The complications of promiscuity: endocannabinoid action and metabolism. British Journal of Pharmacology. 152(5), 602-623
• WILKINSON, J D, KENDALL, D A and RALEVIC, V, 2007. Delta 9-tetrahydrocannabinol inhibits electrically-evoked CGRP release and capsaicin-sensitive sensory neurogenic vasodilatation in the rat mesenteric arterial bed. British Journal of Pharmacology. 152(5), 709-16
• ABDEL-RAZAQ, W, BATES, T E and KENDALL, D A, 2007. The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology. 73(12), 1995-2003
• FINN, D. P., JHAVERI, M. D., BECKETT, S. R.G., MADJD, A., KENDALL, D. A., MARSDEN, C. A. and CHAPMAN, V., 2006. Behavioral, central monoaminergic and hypothalamo–pituitary–adrenal axis correlates of fear-conditioned analgesia in rats Neuroscience. 138(4), 1309-1317
• O'SULLIVAN, S.E., KENDALL, D.A. and RANDALL, M.D, 2006. Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol. Journal of Pharmacology and Experimental Therapeutics. 317(1), 428-438
• MILLNS,P.J., CHIMENTI,M., ALI,N., RYLAND,E., DELAGO,E., FERNANDEZ-RUIZ,J., CHAPMAN,V. and KENDALL,D.A, 2006. Effects of inhibition of fatty acid amide hydrolase versus the anandamide membrane transporter on TRPV1 mediated calcium responses in adult DRG neurones; the role of CB1 receptors European Journal of Neuroscience. 24(12), 3489-3495
• O'SULLIVAN, S.E., TARLING, E.J., BENNETT, A.J., KENDALL, D.A. and RANDALL, M.D, 2005. Novel time-dependent vascular actions of Delta9-tetrahydrocannabinol mediated by peroxisome proliferator-activated receptor gamma. Biochemical and Biophysical Research Communications. 337(3), 824-831
• O'SULLIVAN, S.E., KENDALL, D.A. and RANDALL, M.D, 2005. Vascular effects of delta 9-tetrahydrocannabinol (THC), anandamide and N-arachidonoyldopamine (NADA) in the rat isolated aorta. European Journal of Pharmacology. 507(1-3), 211-221
• DE BANK, P.A.., KENDALL, D.A. and ALEXANDER, S.P.H, 2005. A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening Biochemical Pharmacology. 69(8), 1187-1193
• SAGAR, D.R., KELLY, S., MILLNS, P.J., O'SHAUGHNESSEY, C.T., KENDALL, D.A. and CHAPMAN, V, 2005. Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats. European Journal of Neuroscience. 22(2), 371-379
• PARDON, M C, ROBERTS, R E, MARSDEN, C A, BIANCHI, M, LATIF, M L, DUXON, M S and KENDALL, D A, 2005. Social threat and novel cage stress-induced sustained extracellular-regulated kinase1/2 (ERK1/2) phosphorylation but differential modulation of brain-derived neurotrophic factor (BDNF) expression in the hippocampus of NMRI mice. Neuroscience. 132(3), 561-74
• RICHARDS, J. K., ABDEL-RAZAQ, W., BATES, T. E. and KENDALL, D. A., 2005. The effects of desmethylimipramine on cyclic AMP-stimulated gene transcription in a model cell system Biochemical Pharmacology. 70(5), 762-769
• YATES, A.S., DOUGHTY, S.W., KENDALL, D.A. and KELLAM, B., 2005. Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB₂ receptor Bioorganic & Medicinal Chemistry Letters. 15(16), 3758-3762
• O'SULLIVAN, S.E., KENDALL, D.A and RANDALL, M.D, 2005. The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. British Journal of Pharmacology. 145(4), 514-526
• JHAVERI, MAULIK D, ELMES, STEVEN J R, KENDALL, DAVID A and CHAPMAN, VICTORIA, 2005. Inhibition of peripheral vanilloid TRPV1 receptors reduces noxious heat-evoked responses of dorsal horn neurons in naïve, carrageenan-inflamed and neuropathic rats. European Journal of Neuroscience. 22(2), 361-70
• DALEY, E., WILKIE, D., LOESCH, A., HARGREAVES, I. P., KENDALL, D. A., PILKINGTON, G. J. and BATES, T. E., 2005. Chlorimipramine: A novel anticancer agent with a mitochondrial target Biochemical and Biophysical Research Communications. VOL 328(NUMBER 2), 623-632
• GOLDRING, W. P., ALEXANDER, S. P., KENDALL, D. A. and PATTENDEN, G., 2005. Novel phomactin analogues as PAF receptor ligands Bioorganic and Medicinal Chemistry Letters. VOL 15(NUMBER 13), 3263-3266
• ELMES, STEVEN J R, WINYARD, LISA A, MEDHURST, STEPHEN J, CLAYTON, NICK M, WILSON, ALEX W, KENDALL, DAVID A and CHAPMAN, VICTORIA, 2005. Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat. Pain. 118(3), 327-35
• FINN, D P, BECKETT, S R G, ROE, C H, MADJD, A, FONE, K C F, KENDALL, D A, MARSDEN, C A and CHAPMAN, V, 2004. Effects of coadministration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain. European Journal of Neuroscience. 19(3), 678-86
• CHOUDHURY, A.I., SIMS, H.M., HORLEY, N.J., ROBERTS, R.A., TOMLINSON, S.R., SALTER, A.M., BRUCE, M., SHAW, P.N., KENDALL, D., BARRETT, D.A. and BELL, D.R., 2004. Molecular analysis of peroxisome proliferation in the hamster. Toxicology and Applied Pharmacology. 197(1), 9-18
• PARDON, M.-C., KENDALL, D. A., PEREZ-DIAZ, F., DUXON, M.S. and MARSDEN, C.A, 2004. Repeated sensory contact with aggressive mice rapidly leads to an anticipatory increase in core body temperature and physical activity that precedes the onset of aversive responding. European Journal of Neuroscience. 20(4), 1033-1050
• DUNCAN, M., KENDALL, D.A. and RALEVIC, V, 2004. Characterization of cannabinoid modulation of sensory neurotransmission in the rat isolated mesenteric arterial bed. Journal of Pharmacology and Experimental Therapeutics. 311(1), 411-419
• LEGGETT, J.D., ASPLEY, S, BECKETT, S.R.G., D'ANTONA, A.M., KENDALL, D.A. and KENDALL, D.A, 2004. Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors. British Journal of Pharmacology. 141(2), 253-262
• FINN, D. P., BECKETT, S. R.G., RICHARDSON, D., KENDALL, D. A., MARSDEN, C. A. and CHAPMAN, V., 2004. Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors European Journal of Neuroscience. 20(3), 848-852
• SAGAR, D. R., SMITH, P. A., MILLNS, P. J., SMART, D., KENDALL, D. A. and CHAPMAN, V., 2004. TRPV1 and CB1 receptor-mediated effects of the endovanilloid/endocannabinoid N-arachidonoyl-dopamine on primary afferent fibre and spinal cord neuronal responses in the rat European Journal of Neuroscience. 20(1), 175-184
• O'SULLIVAN, S.E., KENDALL, D.A. and RANDALL, M.D, 2004. Heterogeneity in the mechanisms of vasorelaxation to anandamide in resistance and conduit rat mesenteric arteries. British Journal of Pharmacology. 142(3), 435-42
• O'SULLIVAN, S.E., KENDALL, D.A. and RANDALL, M.D, 2004. Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA). British Journal of Pharmacology. 141(5), 803-812
• DUNCAN, MARNIE, MILLNS, PAUL, SMART, DARREN, WRIGHT, JAMES E, KENDALL, DAVID A and RALEVIC, VERA, 2004. Noladin ether, a putative endocannabinoid, attenuates sensory neurotransmission in the rat isolated mesenteric arterial bed via a non-CB1/CB2 G(i/o) linked receptor. British Journal of Pharmacology. 142(3), 509-18
• JEFFERY, B., CHOUDHURY, A.I., HORLEY, N., BRUCE, M., TOMLINSON, S.R., ROBERTS, R.A., GRAY, T.J.B., BARRETT, D.A., SHAW, P.N., KENDALL, D. and BELL, D.R., 2004. Peroxisome proliferator activated receptor α regulates a male-specific cytochrome P450 in mouse liver. Archives of Biochemistry and Biophysics. 429(2), 231-236
• ELMES, S.J.R., JHAVERI, M.D., SMART, D., KENDALL, D.A. and CHAPMAN, V, 2004. Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain. European Journal of Neuroscience. 20(9), 2311-2320
• RANDALL, M. D., KENDALL, D. A. and O SULLIVAN, S., 2004. The complexities of the cardiovascular actions of cannabinoids British Journal of Pharmacology. VOL 142(PART 1), 20-26
• FINN, DAVID P, JHAVERI, MAULIK D, BECKETT, SIMON R G, KENDALL, DAVID A, MARSDEN, CHARLES A and CHAPMAN, VICTORIA, 2004. Cannabinoids modulate ultrasound-induced aversive responses in rats. Psychopharmacology. 172(1), 41-51
• PATKAR, ASHWIN A, MARSDEN, CHARLES A, NAIK, PRAKASH C, KENDALL, DAVID A, GOPALAKRISHNAN, RAMAN, VERGARE, MICHAEL J and WEINSTEIN, STEPHEN P, 2004. Differences in peripheral noradrenergic function among actively drinking and abstinent alcohol-dependent individuals. American Journal of Addictions. 13(3), 225-35
• ELMES, STEVEN J R, MILLNS, PAUL J, SMART, DARREN, KENDALL, DAVID A and CHAPMAN, VICTORIA, 2004. Evidence for biological effects of exogenous LPA on rat primary afferent and spinal cord neurons. Brain Research. 1022(1-2), 205-13
• PINTHONG, DARAWAN, SONGSERMSAKUL, PIYADA, RATTANACHAMNONG, PIYANEE and KENDALL, DAVID A, 2004. The effects of imidazoline agents on the aggregation of human platelets. Journal of Pharmacy and Pharmacology. 56(2), 213-20
• DE BANK, P.A., KELLAM, B., KENDALL, D.A. and SHAKESHEFF, K.M., 2003. Surface engineering of living myoblasts via selective periodate oxidation Biotechnology and Bioengineering. 81(7), 800-808
• KELLY, S., JHAVERI, M.D., SAGAR, D.R., KENDALL, D.A. and CHAPMAN, V., 2003. Activation of peripheral cannabinoid CB₁ receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation European Journal of Neuroscience. 18(8), 2239-2243
• DICKENSON, J.M., REEDER, S., REES, B., ALEXANDER, S. and KENDALL, D., 2003. Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106 European Journal of Pharmacology. 474(1), 43-51
• TEP-AREENAN, P., KENDALL, D. A. and RANDALL, M. D., 2003. Mechanisms of vasorelaxation to testosterone in the rat aorta European Journal of Pharmacology. VOL 465(NUMBER 1-2), 125-132
• TEP-AREENAN, P., KENDALL, D. A. and RANDALL, M. D., 2003. Mechanisms of vasorelaxation to 17b-oestradiol in rat arteries European Journal of Pharmacology. VOL 476(NUMBER 1-2), 139-149
• FINN, D P, JHAVERI, M D, BECKETT, S R G, ROE, C H, KENDALL, D A, MARSDEN, C A and CHAPMAN, V, 2003. Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology. 45(5), 594-604
• SOKAL, D M, ELMES, S J R, KENDALL, D A and CHAPMAN, V, 2003. Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. Neuropharmacology. 45(3), 404-11
• PINTHONG, D., KENDALL, D. A., MACLENNAN, S. J., EGLEN, R. M. and WILSON, V. G., 2003. No Evidence for Activation of alpha~2-Adrenoceptors by Methanolic Extracts of Bovine Brain and Lung Containing Clonidine-Displacing Substance Annals of the New York Academy of Sciences. VOL 1009, 201-215
• CHEER, J F, KENDALL, D A, MASON, R and MARSDEN, C A, 2003. Differential cannabinoid-induced electrophysiological effects in rat ventral tegmentum. Neuropharmacology. 44(5), 633-41
• PINTHONG, D, KENDALL, D A and WILSON, V G, 2003. Complex interaction of alpha(2)-adrenoceptor binding sites with bovine brain and lung extracts containing clonidine-displacing substance. Annals of the New York Academy of Sciences. 1009, 216-21
• KENNY, L.C., BAKER, P.N., KENDALL, D.A., RANDALL, M.D. and DUNN, W.R, 2002. Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsia. Clinical Science. 103(1), 67-73
• HARRIS, D., MCCULLOCH, A.I., KENDALL, D.A. and RANDALL, M.D, 2002. Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. Journal of Physiology. 539(3), 893-902
• KENNY, L.C., BAKER, P.N., KENDALL, D.A., RANDALL, M.D. and DUNN, W.R, 2002. The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women British Journal of Pharmacology. 136(8), 1085-1088
• TEP-AREENAN, P., KENDALL, D.A. and RANDALL, M.D, 2002. Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels. British Journal of Pharmacology. 135(3), 735-740
• RALEVIC, VERA and KENDALL, DAVID A, 2002. Cannabinoids inhibit pre- and postjunctionally sympathetic neurotransmission in rat mesenteric arteries. European Journal of Pharmacology. 444(3), 171-81
• SHAKESHEFF, K.M., SILVA, M., HOWDLE, S.M., SALEM, A.K., ROSE, F.R., WHITAKER, M.J., WOOD, I., DE BANK, P., KENDALL, D.A. and KELLAM, B., 2002. Delivering protein and cell therapeutics for tissue regeneration In: International Symposium on Recent Advances in Drug Delivery Systems.
• RANDALL, M. D., HARRIS, D., KENDALL, D. A. and RALEVIC, V., 2002. Cardiovascular effects of cannabinoids Pharmacology and Therapeutics. VOL 95(NUMBER 2), 191-202
• KENDALL,D.A. and ALEXANDER,S.P., 2002. Cannabinoid receptors. In: Understanding G protein-coupled receptors and their role in the CNS Oxford University Press.
• RALEVIC, VERA, KENDALL, DAVID A, RANDALL, MICHAEL D and SMART, DARREN, 2002. Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: roles in regulation of cardiovascular function. Life Sciences. 71(22), 2577-94
• MILLNS, P.J., CHAPMAN, V. and KENDALL, D.A, 2001. Cannabinoid inhibition of the capsaicin-induced calcium response in rat dorsal root ganglion neurones. British Journal of Pharmacology. 132(5), 969-971
• RALEVIC, V and KENDALL, D A, 2001. Cannabinoid inhibition of capsaicin-sensitive sensory neurotransmission in the rat mesenteric arterial bed. European Journal of Pharmacology. 418(1-2), 117-25
• RALEVIC, V, KENDALL, D A, JERMAN, J C, MIDDLEMISS, D N and SMART, D, 2001. Cannabinoid activation of recombinant and endogenous vanilloid receptors. European Journal of Pharmacology. 424(3), 211-9
• RALEVIC, V, KENDALL, D A, JERMAN, J C, DAVIS, J B, MIDDLEMISS, D N and SMART, D, 2001. Low pH modulation of recombinant vanilloid receptors and perivascular capsaicin-sensitive sensory neurotransmission. Autonomic Neuroscience. 88(1-2), 36-44
• The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms British Journal of Pharmacology. (In Press.)