Contact
Biography
Zhi Yuan obtained his Masters of Pharmacy (MPharm) and Ph.D. degree in the field of medicinal chemistry at the University of Nottingham (UoN), the latter of which funded by the prestigious UoN Vice Chancellor's Scholarship for Research Excellence. After spending just under 3 years as a medicinal/organic chemist collectively at Sygnature Discovery in Nottingham and Nanyang Technological University in Singapore, Zhi Yuan rejoins the University of Nottingham Malaysia as an assistant professor. Apart from being a keen chemist, Zhi Yuan has a strong interest in G-protein coupled receptors (GPCRs) and novel antimicrobial discovery, as well as exploring the development and wider use of fluorescent compounds for the understanding of biological processes and drug development purposes.
Expertise Summary
- Medicinal Chemistry
- Synthetic Organic Chemistry
Teaching Summary
Subject areas of competence: Medicinal chemistry, organic chemistry, molecular pharmacology
Module convener/contributor for the modules:
Bachelor of Pharmacy: PHAR1038 (Bacterial and Fungal Infections), PHAR2040 (Cardiovascular)
Master of Pharmacy: PHAR1034 (Human Life Cycle), PHAR2044 (Infections 1), PHAR2045 (Infections 2), PHAR2051 (Cardiovascular)
Pharmaceutical and Health Sciences: PHAR1026 (Pharmaceutical and Biological Chemistry), PHAR2010 (Pharmaceutical Analysis and Spectroscopy), PHAR3014 (Medicinal Chemistry and Drug Design)
Recent Publications
ZHANG, BO, LU, DERONG, WANG, DENNIS BAO RONG, KOK, ZHI YUAN, CHAN-PARK, MARY B. and DUAN, HONGWEI, 2024. Enzyme-Responsive Polyion Complex Nanoparticles of Cationic Antimicrobials for Activatable Antibacterial Therapy Advanced Functional Materials. n/a(n/a), 2407869. IF (2022): 19.0; T10 MELVIN YONG, ZHI Y. KOK, CHONG H. KOH, WENBIN ZHONG, JUSTIN TY. NG, YUGUANG MU, MARY B. CHAN-PARK and YUNN-HWEN GAN, 2023. Membrane Potential-Dependent Uptake of Cationic Oligoimidazolium Mediates Bacterial DNA Damage and Death Antimicrobial Agents and Chemotherapy. 0(0), e00355-23. IF (2022): 4.9; Q1 KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MOCKING, TAMARA A. M., VISCHER, HENRY F., LEURS, ROB, HILL, STEPHEN J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2022. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor Journal of Medicinal Chemistry. 65(12), 8258-8288. IF (2022): 7.3; T10 KOK, ZHI YUAN, STODDART, LEIGH A., MISTRY, SARAH J., MISTRY, SHAILESH N. and KELLAM, BARRIE, 2019. Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H1 Receptor In: 27th Annual GP2A Medicinal Chemistry Conference, August 2019, Nottingham, United Kingdom.